2017 projectsFundingChief investigator
The PEPTIC study$25,000Dr Paul Young
Pharmacokinetics of Transdermal Nicotine in the ICU. (Malcolm Fisher Intensive Care Foundation Grant)$40,000A/Professor Jeremy Cohen
Liberal glucose Control in critically ill patient with pre-existing type 2 Diabetes (LUCID). (Fisher & Paykel Research Project Grant)$25,000A/Professor Adam Deane
Optimising antibiotic dosing for the treatment and prevention of central nervous system infections in critically ill patients. (Smiths Medical Research Project Grant)$35,000Mr Nilesh Kumta
Asymptomatic hypoglycaemia and cardiac rhythm disturbances in survivors of critical illness with type 2 diabetes: The HOLTER study$26,000Dr Yasmine Ali Abdelhamid
Burnout in critical care health-care professionals. (Knapp Family Research Project Grant)$25,000A/Professor Diane Chamberlain
Trainee Project Grants:
The effect of light and lipid on the degradation of micronutrients in total parenteral nutrition infused over 24 hours – a bench study.$5,000Dr Joanna Longley
2016 projectsFundingChief investigator
Age-specific reference ranges for coagulation assays in Australian children. (Getinge Group Research Project Grant)$11,500Dr Katie Moynihan
A safety and feasibility randomised, controlled trial comparing denosumab to placebo in critically ill patients at risk of accelerated bone loss. (Malcolm Fisher Intensive Care Foundation Grant)$14,638A/Professor Neil Orford
Accuracy of transcutaneous oxygen saturation in critically ill children – a prospective observational study. (Fisher & Paykel Research Project Grant)$18,000A/Professor Andreas Schibler
PROMOTE-SAH: A prospective multicentre observational study of aneurysmal subarachnoid haemorrhage in Australasian intensive care. (Medtronic Research Project Grant)$46,571A/Professor Andrew Udy
Sleep monitoring techniques in ICU: Can motion accelerometers be proxy measures of sleep? (Knapp Family Research Project Grant)$12,310Ms Lori Delaney
ADRENAL-HEOR: Adjunctive corticosteroid treatment in critically ill patients with septic shock – health economics and outcomes research. (Teleflex Research Project Grant)$34,000Ms Kelly Thompson
Long-term outcomes after critical illness in children. (Mallinckrodt Research Project Grant)$15,000A/Professor Luregn Schlapbach
2015 projectsFundingChief investigator
Parent initiated response to escalate care of the deteriorating child: the PARTNER project$19,205Dr Fenella Gill
Novel methods of measuring physical function in ICU survivors (Malcolm Fisher ICF Grant)$35,000Dr Elizabeth Skinner
Induced hypernatremia – a therapy for acute lung injury? HALT study (Fisher & Paykel Research Grant)$32,780Prof. Andrew Bersten
A pilot, randomised, unblinded feasibility, safety and biochemical and physiological efficacy study of 20% vs 4% human albumin solution for fluid bolus therapy in critically ill adults (Baxter Healthcare Novice Research Grant)$18,928Dr Johan Martensson
Levetiracetam pharmacokinetics in critically ill patients with severe traumatic brain injury and subarachnoid haemorrhage$35,000Mr Menino Osbert Cotta
Survivors of ICU with diabetes type 2 and the effect of shared care follow up clinics: The SWEET-AS feasibility study$35,000Dr Yasmine Ali Abdelhamid
Targeted temperature management for traumatic brain injury: a feasibility study of strict normothermia (Knapp Family Research Grant)$24,080Dr Manoj Saxena
Randomised controlled feasibility trial of conservative vs usual fluid management in critically ill adults$34,000A/Prof. David Gattas
Trainee Project Grants:
Effect of deferoxamine on iron levels and in vitro microbial growth associated with red blood cell transfusion in a canine model of haemorrhagic shock: A randomised controlled trial.$5,000Dr Damian Bradley
Functional outcomes of the elderly (65 years and older) following admission to the Flinders Medical Centre (FMC) Intensive Care Unit (ICU).$5,000Dr Kristin Hayres
2014 projectsFundingChief investigator
Pharmacokinetic Australasian Collaborative$39,156Prof. Jeffrey Lipman
TxA levels in the PATCH-TRAUMA trial$38,350Prof. Michael Read
Incidence, Risk Factors, Consequences and Treatment of Ventilated Patients with Nosocomial Infection with Pandrug Resistant Organisms in Hospitals in Asia (Fisher & Paykel Research Grant)$34,000Dr Steve McGloughlin
The peptic study$25,000Dr Paul Young
Can individualized blood pressure targets reduce the risk of new onset acute kidney injury among critically ill patients with shock – a pilot before and after feasibility study$22,800Dr Rakshit Panwar
Identifying the Genetic Cause of Fatal Pseudomonas$15,062Dr Luregn Schlapbach
Central venous Access device SeCurement And Dressing Effectiveness: the CASCADE pilot trial$12,240A/Prof. Marion Mitchell
A Discrete Choice Experiment to evaluate clinician preference regarding resuscitation fluid selection$9,500Mrs Naomi Hammond
Haemodynamic Effects of Intravenous Paracetamol in Healthy Volunteers$7,814Ms Elizabeth Chiam
Trainee Project Grants:
Gallbladder Motility in Critical Illness$5,000Dr Mark Plummer
The Endothelial Glycocalyx in Acute Traumatic Coagulopathy$3,400Dr Elissa Milford
2013 projectsFundingChief investigator
Intestinal GLP-2 as novel target in critical illness-induced malabsorption.$30,900Dr Richard Young
ADRENAL Consent Study – a multi-centre, prospective, observational study of the process of obtaining consent from potential participants or their substitute decision-makers in the adjunctive corticosteroid treatment in critically ill patients with septic shock. $5,000Ms Heidi Buhr
Endothelin blockade in ex-vivo lung perfusion $25,000Dr Ryan Watts
Gene expression profiling in critically ill patients with septic shock: a pilot study. $11,625Dr Jeremy Cohen
Vitamin D dosing study in Intensive Care Unit patients with SIRS. $29,000Dr Priya Nair
Therapeutic hypercapnia after cardiac arrest, a multi-centre pilot feasibility and safety randomized controlled trial.$13,320Dr Glenn Eastwood
Prophylactic intra-aortic balloon counterpulsation in high-risk cardiac surgery: The PINBALL Pilot Randomised Controlled Trial. $34,000Dr Ed Litton
Hydrogen sulfide and substance P: novel biomarkers for sepsis.$26,000A/Prof. Geoffrey Shaw
2012 projectsFundingChief investigator
The HEAT trial – a randomised placebo-controlled trial of intravenous paracetamol in febrile septic patients (Wellington Regional Hospital)$20,000Dr Paul Young
Endotoxemic rodent diastolic dysfunction (Mater Health Services) Dr David Sturgess $20,000Dr David Sturgess
Pathology of the kidney in septic renal failure (Royal Adelaide Hospital) $20,000Dr Matthew Maiden
ASAP-ECMO: understanding altered pharmacokinetics to improve patient outcomes (The Prince Charles Hospital) Dr Kiran Shekar $30,000Dr Kiran Shekar
Physiological and functional outcomes following early rehabilitation in sepsis (Royal Brisbane & Women’s Hospital) $10,000Dr Jennifer Paratz
“Conservative” or “liberal” oxygen targets in mechanically ventilated patients – a pilot feasibility study (John Hunter Hospital) $15,000Dr Rakshit Panwar
Relationship between serum 1,25(OH)D3 and inflammation and organ failure in critically ill patients with severe sepsis (Princess Alexandra Hospital) $15,000Professor Bala Venkatesh
ICU anxiety and emotional recovery (Princess Alexandra Hospital) $11,100Maria Isabel Castillo Escobar
2011 projectsFundingChief investigator
TEAM: Trial of early activity and mobility in ICU (Alfred Hospital, VIC) $45,000Dr Carol Hodgson
Early intervention to prevent muscle weakness in intensive care: a pilot randomised controlled trial (Austin Hospital, VIC) $40,000Dr Sue Berney
Prevention of Ventilator Associated Pneumonia by Inhaled Heparin (IPHIVAP) (Royal Brisbane and Women’s Hospital, QLD) $35,000Associate Professor Rob Boots
A prospective, observational study of critical illness related changes in bone mineral density, bone turnover and calcium metabolism (Barwon Health, VIC) $28,000Dr Neil Orford
Do thromboelastometric parameters change with increasing degree of sepsis related organ failure? (Flinders Medical Centre, SA) $12,000Dr Shivesh Prakash
Disposition of sedative, analgesic and antibiotic drugs during simulated extracorporeal membrane oxygenation (Prince Charles Hospital, QLD). $12,000Dr Kiran Shekar.
Effect of ECMO on long term disability in severe ARDS (Alfred Hospital, VIC). $10,000Dr Vincent Pellegrino
Post Resuscitation fluid boluses In severe sepsis or septic shock prevalence and Efficacy (PRICE study) (Flinders Medical Centre, SA). $7,000Dr Shailesh Bihari
2010 projectsFundingChief investigator
Critical Illness & Intestinal Sweet Taste Receptors. Royal Adelaide Hospital.$45,600Dr Adam Deane
Acute kidney injury: Investigating treatments and finding new markers for its early detection in patients with traumatic brain injury. ANZICRC /Monash University. $13,553Prof Rinaldo Bellomo
Improving Sleep for ICU Patients. University of Technology, Sydney.$15,714Rosalind Elliott
A Life cycle assessment comparing single-use with disposable central venous catheter tray sets. Western Health.$11,000Dr Forbes McGain
Care after death: An exploration of nursing care of the bereaved family in ICU. Monash University.$11,490Ms Melissa Bloomer
The ANZICS CTG Point Prevalence Program. ANZICS CTG.$31,000Dr Ian Seppelt
Magnitude and factors contributing to functional impairment among Acute Lung Injury survivors following discharge from an acute care facility. University of Newcastle / John Hunter Hospital.$9,643Jenny Mackney
ICU Liaison Practice Variation Study. Western Health.$12,000Anna Green
2009 projectsChief investigator
A randomised controlled study comparing the effect of two different anticoagulation regimens on filter life during Continuous Renal Replacement Therapy (CRRT) – The Heparin Citrate (THC) Study.Dr David Gattas
Development of a new hyperosmolar solution for use in Neurotrauma.A/Prof Hayden White
MRI determination of renal blood flow during Acute Renal Failure in critically ill patients. Prof Ronaldo Bellomo
Pilot RCT of Continuous Beta-lactam infusion compared with intermittent dosing in critically ill patients. Prof Jeffrey Lipman
PCT guided antibiotic decision makling in ICU. A/Prof Yahya Shehabi
The efficacy, cost effectiveness, and environmental impact of Selective Decontamination of the Digestive tract in critically ill patients treated in the Intensive Care Unit (The SuDDICU study).Dr Ian Seppelt
Patient comfort and safety practices in ICU.Prof D Elliott
2008 projectsChief investigator
Compliance with Processes of Care in the Intensive Care Unit.Dr Tony Burrell
Economic Evaluation of Resuscitation in Sepsis.Professor Rinaldo Bellomo
The RELEVANT Study. Professor D J (Jamie) Cooper
Mapping ICU Liaison Nurse Services in Australia.Suzanne Eliott
An Audit of the Time and Costs involved in the Ethical and Governance Review Process of a Multi-Centre Clinical Trial in Australia and New Zealand – TAME Study (Time and Money Evaluation).Belinda Howe
Impact of the Intensive Care Discharge Process on Patient Outcomes.A/Prof John Santamaria
The effect of varying arterial carbon dioxide concentrations (PaCo2) within the normocapnic range on brain tissue oxygenation and microdialysis markers of cell injury in severe traumatic brain injury.Professor David James Cooper
The ANZICS Clinical Trials Group Point Prevalence Program.Dr Ian Seppelt
Haemodynamic Effects of Paracetamol.Susan Kelly
2007 projectsChief investigatorStatus
Bicarbonate in cardiac surgery.Prof Rinaldo BellomoIn progress
Heparin in severe sepsis: IL-6 as a marker of efficiency.Dr Alistair NicholCompleted
Optimal ventilation (PHARLAP) in acute lung injury.Prof D. James (Jamie) CooperIn progress
Nutritional therapy of severe acute pancreatitis.Dr Andrew DaviesIn progress
Reducing CSF sampling frequency to minimise ventriculitis. A/Prof Gavin LeslieIn progress
Western Australia Outcome Obtained by Linkage – A study of feasibility. Clin A/Prof Steve WebbCommencing
2006 projectsChief investigatorStatus
Aminophylline in Severe Bronchiolitis.Dr Rob HenningIn progress
The Australasian Resuscitation is Sepsis Evaluation (ARISE).Peake, SCompleted
Heparin in Severe Sepsis.Robertson, MIn progress
Hypothermia in Traumatic Brain Injury in Children (HiTBIC).Beca, JIn progress
New Insights into Brain Injury in Infants Undergoing Surgery for Congenital Heart Disease.Sherkerdemian, LIn progress
Probiotics & Enteral Nutrition Reducing Diarrhoea in ICU. Leanne, JIn progress
2005 projectsChief investigatorStatus
A Routine Daily Interruption to Sedation (AROUSE).Weisbrodt, LCompleted
A Trial of Nebulised Heparin in Acute Lung Injury. Dixon, BCompleted
Low-dose angiotesin II in experimental early and sustained septic renal dysfunction (Angiotensin II in experimental septic acute renal failure).Bellomo, RCompleted
RADICAL Iredell, JCompleted
Ventilation and Weaning Practices in Australia & New Zealand.Rose, LCompleted
2004 projectsChief investigatorStatus
Bispectral Index-Guided Sedation as Compared to Standard Practice of Sedation in PICU: A Prospective, Randomised, Single Blind Experimental Study.Ramelet, A
Early Nasojejunal Tube to meet Energy Requirements in Intensive Care study (The ENTERIC study).Davies, AIn progress
Lung Injury Associated with Cardiac Surgery.Dixon, B
Preoperative Intravenous N-Acetylcsteine for the Prevention of Renal Failure in Patients with Renal Impairment Undergoing Cardiac Surgery.Shehabi, YCompleted
Review of Retrieval Services for the Critically Ill.Flabouris, ACurrent
The effect of N-Acetylcysteine on renal function after cardiopulmonary bypass guidelines for nutritional support in the intensive care.Bellomo, RCompleted and Published
2003 projectsChief investigatorStatus
A Prospective Study of Non-Invasive Ventilation in Patients with Acute Respiratory Failure in Australia.Bersten, A
Effectiveness of the Medical Emergency Team: a randomised clinical trial.Hilman, KCompleted and Published
Kidney and Brain bioenergetics in Severe Sepsis.Bellomo, R
Profiles of Gradated Compression Stockings in Intensive Care.Limpus, A
Scheduled Antibiotic Cycling in Intensive Care.Iredell, J
2002 projectsChief investigatorStatus
Developing and Evaluating Evidence-Based Guidelines for Nutritional Support in the Intensive Care Unit.Doig, GCompleted
Early Decompressive Craniectomy in Brain Injury (DECRA).Cooper, DJIn progress
Relationship Between Tissue Hypoxia and Apoptosis.Venkatesh, B
2001 projectsChief investigator
Therapeutic Strategies in Severe Smoke Inhalation. Fraser, J
2000 projectsChief Investigator
Tissue Oxygenation During Endotoxaemia.Venkatesh, B
1999 projectsChief Investigator
Vasoactive Drugs and Regional Circulations.Bellomo, R
1998 projectsChief InvestigatorStatus
Hypertonic Saline in Head Injured Trauma Patients – a prospective controlled clinical trial.Cooper, DJCompleted and Published
1997 projectsChief Investigator
Investigate Haemodynamic and Respiratory Effects of Pressure-Support Ventilation.Raper, R
Using Endotoxin Tolerance to Treat Septic Shock.Presneill, J
1996 projectsChief Investigator
The effects of high volume mechanical ventilation on systemic inflammation in an animal model of pneumonia.Bernsten, AD
Combination Anti-cytokine Therapy in Septic Shock.Peake, S
1995 projectsChief Investigator
Nitric Oxide in Acute Brain Injury.Finfer, S
1994 projectsChief Investigator
Rapid Detection of Gram Negative Sepicaemia by PCR.Corke, C
Role of Endothelin-1 in the Hypoxic Pulmonary Vascular Response to Acute Respiratory Failure.Watkins, N